Genital Warts caused by HPV – treatment, recurrence, research 2018

What should you know about genital warts caused by HPV?

Anogenital warts typically develop approximately 2–3 months after HPV infection (almost all caused by types 6 or 11); however, not all persons infected with HPV types 6 and 11 develop genital warts. Anogenital warts should be assessed by a clinician and can be treated, although many warts (20–30%) regress spontaneously. Recurrence of anogenital warts within 3 months is common (approximately 30%), whether clearance occurs spontaneously or following treatment.

Read the whole manual about HPV and genital warts:

https://www.cdc.gov/vaccines/pubs/surv-manual/chpt05-hpv.html

What is the most effective treatment against genital warts?

The most effective treatment (with the lowest recurrences) is called Photodynamic Therapy. Unfortunately this treatment is not available in the Western world. I mean: it is possible to get Photodynamic Therapy against i.e. ACNE on face, but it’s not possible to get it against genital warts. Why? I have no idea. Maybe it is a some kind of conspiracy? Anyway the fact is one: HPV virus hides in the skin, and it is possible to eradicate it during a few ALA-PDT treatments.

There were many clinical trials about Photodynamic therapy, but usually in China. You can check this PDF file:

https://www.cdc.gov/std/tg2015/evidence-tables/hpvtableevidence-genitalwarts-2015.pdf

What is the biggest problem with genital warts?

The biggest problem with genital warts is that they can come back, especially in the first months after their show up. All available methods (Cryotherapy, Podophyllotoxin, Aldara, Veregen…) have high recurrence rates.

What can you do to lower genital warts recurrence rate?

You can take medicinal mushrooms to boost your immune system (for example:  Coriolus versicolor and Reishi had 88% clearance rate after 2 months, during one clinical trial).

You can try food supplements like Ellagic Acid and Annona Muricata extract.  In one clinical trial EA+AM gave 74% HPV clearance rate after 6 months.

You can try use Panavir gel topically. Panavir is an antiviral medicine created in Russia. It works antiviral and immunostimulating. There are many russian clinical trials about its effectiveness.

http://poi555.com/2018/01/panavir-from-russia-alternative-treatment-for-hpv-and-genital-warts/

You can try hypethermia (44-45 celsius degree) on your genitals, but it might be hard to get this treatment in any clinic.

You can combine removing warts with taking Inosine Pranobex (3g daily for 4 weeks).

If you have strong recurrences – you should check your glucose level in blood. If you have diabetes, then you should know that there is correlation between the strength of HPV/number of recurrences and diabetes.

So what can you do?

Option A:

You can go to China and try to get Photodynamic Therapy (ALA-PDT) against genital warts. That’s the most expensive option.

Option B:

You can try Cryotherapy or Podophyllotoxin, and be mentally prepared for recurrences.

Option C:

You can try Cryotherapy or Podophyllotoxin, and 1 immune-booster (i.e. medicinal mushrooms, Ellagic acid + Annona Muricata extract)

Option D:

You can try Cryotherapy or Podophyllotoxin, 1 immune-booster and – topically – Panavir gel. Panavir gel should be applied 2 times daily (5 days before the treatment, 10 days after the treatment).

YOU CAN BUY PANAVIR AT OTC ONLINE STORE

Option E:

Combine Cryotherapy or Podophyllotoxin with Inosine Pranobex: 3g daily (1g in the morning/afternoon/evening) for 4 weeks. If you do this, then the chances for recurences are as low as 6-7%.

What about ALDARA?

If you are a man, then it’s a total waste of time.
If you are a woman, then you can try it (it has 60% effectiveness in females).

What about ACV, Thuja, homeopathic medicines?

Forget about it. It’s your health. Don’t waste your time on methods without any clinical trials. You can check Google Scholar and search for clinical trials.

Natural HPV treatment: Ellagic acid and Annona Muricata – strong antiviral herbs

It seems that we have a new natural treatment for HPV infections.

Journal of Functional Foods published article “Antiviral activity of Ellagic acid and Annona Muricata in cervical HPV related pre-neoplastic lesions: A randomized trial” about Ellagic acid and Annona Muricata, two natural ingredients that fights with HPV virus:

Ellagic acid (EA) and Annona Muricata (AM) have antioxidant, anticarcinogenic and antiviral activity demonstrated by in vitro models. This pilot study investigated the in vivo potential anti-viral activity in women affected by Low squamous intraepithelial lesion (L-SIL) related to high risk human papilloma virus (HR-HPV), and the ability to modify the oncoproteins expression in the cervical lesion thickness. Sixty women affected by HR-HPV related L-SIL, were randomly divided into two groups: group A (n = 30) supplemented with EA (16 mg) + AM (100 mg) 2 times daily for 6 months and group B (n = 30) administered with placebo. HR-HPV clearance was obtained in 74% of cases in group A compared to 25% of cases in group B (p = 0.001) and p21 expression in LSIL thickness increased in 63.2% of cases in group A compared to 20% in group B (p = 0.03). AE/AM supplementation significantly induces HR-HPV elimination and stimulates p21 expression in LSIL thickness.

See the whole article:

http://www.sciencedirect.com/science/article/pii/S1756464617303225

So as for now we have at least 2 very effective natural treatments for HPV:
– mushroom extracts from Coriolus Versicolor + Reishi, 88% clearance after 2 months
– Ellagic acid and Annona Muricata, 74% clearance after 6 months

More informations about ellagic acid:

Ellagic acid is a Polyphenol compound found in numerous fruits and vegetables, including, raspberries; strawberries; cranberries; walnuts; pecans; pomegranates; and other plant foods. It is often regarded as an antioxidant. Ellagic Acid Clinical Tests on cultured human cells also show that Ellagic acid prevents the destruction of the p53 gene by cancer cells. Additional studies suggest that one of the mechanisms by which Ellagic acid inhibits mutagenesis and carcinogenesis is by forming adducts with DNA, thus masking binding sites to be occupied by the mutagen or carcinogen.

https://pubchem.ncbi.nlm.nih.gov/compound/ellagic_acid#section=Top

Remember to use EXTRACTS because they have high amounts of active ingredients.

HPV treatment – HPV cure research 2018

Prologue: How to deal with HPV?

A) Don’t PANIC!
B) Learn about HPV from reliable sources, for example:
https://www.cdc.gov/vaccines/pubs/surv-manual/chpt05-hpv.html
C) Don’t waste your money on food supplements without any clinical trials (like Echinacea, Astralagus, Zinc…)
D) REALLY DON’T PANIC 🙂

There is no cure for HPV but you can still fight with the virus.

How to get rid of HPV faster?

1) Quit smoking
2) Quit drinking
3) Check glucose level in your blood – there is a correlation between HPV strength/recurrence of genital warts (if you have HPV6/11) and diabetes.
4) Eat healthy food, eat lots of vegetables
5) Lower your sugar/carbohydrates intake. Cancer and HPV love sugar.
6) Exercise 2-3 times per week
7) You can try medicinal mushrooms:
– Coriolus versicolor boost immune system
– Reishi fights directly with HPV* and cancer cells*
– Chaga has strong anti-viral activity

IMPORTANT: buy only alcohol/water reishi extracts because they have active ingredients. Avoid powdered reishi – it’s not better than placebo.

– Lentinan (from shiitake mushrooms) lowers genital warts recurrence

* – In this study, we investigated the effects of the aqueous extracts of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum, obtained from three localities (China; and Morelos and Michoacan, Mexico) on cervical cells transformed by human papillomavirus (HeLa and SiHa) and C-33A cancer cells. The cells were plated in DMEM medium supplemented, and were incubated in the presence of different concentrations of G. lucidum for 24 h. Cell proliferation was determined by MTT colorimetric assay and viability by trypan blue assay. Inhibitory dose was determined (IC50) of the three different extracts of G. lucidum in the culture cell lines mentioned above. The apoptosis process was confirmed by nuclear DNA fragmentation and the cell cycle was determined by flow cytometry. The results showed that aqueous extracts G. lucidum obtained from three localities produced inhibition in the proliferation of VPH transformed cells; they also induced apoptosis and cell cycle arrest in HeLa, SiHa, and C-33A cancer cells. Therefore, it was found that aqueous extracts G. lucidum obtained from three different locations produced inhibitory effect on cancer cells and may have a potential therapeutic use for the prevention and treatment of this disease.

8) Vaccine yourself against HPV – it will not help your current infection, but it can protect you against other HPV strains. The best vaccine is called “Gardasil” and “Gardasil 9”.

How to get rid of genital warts?

You can try:
– Podophyllotoxin (it’s very effective, very fast, but you can get skin infection)
– Imiquimod/Aldara (it’s an immunomodulator, you will wait longer to see the effects; Imiquimod is much less effective in case of men)
– Veregen (it’s a green tea extract, it’s effective but very expensive; you will wait very long to see the effects)
– Panavir (antiviral medicine made in Russia; it’s available i.e. as a gel)
– combine Cryotherapy or Podophyllotoxin with Inosine Pranobex (antiviral medicine)

You can ask your doctor for:
– electrocauterization (it’s painful)
– laser treatment
– cryotherapy (the fastest and the cheapest option)
– photodynamic therapy (the best option but it’s hard to get photodynamic therapy against genital warts; many dermatologists don’t know that photodynamic therapy can be used against genital warts)

In general the best options for HPV are:
– check your glucose level and avoid junk food/sugar
– take medicinal mushrooms – Coriolus versicolor 3g/daily in the morning, Reishi (Lingzhi) 1-2g/daily in the evening.
http://dl.begellhouse.com/journals/708ae68d64b17c52,266d4152107fca7a,3512deba5cc9e72b.html
– take Ellagic acid and Annona Muricata extract (check details below)

In general the best options for HPV genital warts are as above, and additionally:
– use Podophyllotoxin for small warts
– use Cryotherapy for big warts
– try to get Photodynamic Therapy
– try Panavir, it’s very effective in combined therapy, when i.e. Cryotherapy removes the warts, and Panavir lowers the chances of recurrences
– combine Cryotherapy or Podophyllotoxin with Inosine Pranobex

YOU CAN BUY PANAVIR AT OTC ONLINE STORE

2018 UPDATE:

Hyperthermia vs. HPV and genital warts

In the current report, the investigators demonstrate that APOBEC3A and APOBEC3G expression levels are increased in genital warts (condyloma acuminata) compared with normal tissues, in which APOBEC3G is barely detectable (Yang et al., 2017). On heat treatment to 42 °C and 45 °C, there is a significant increase in APOBEC3A and APOBEC3G mRNA transcripts in condyloma acuminate, up to 10-fold. Again, this effect is not observed in normal skin.

Although hyperthermia is not as widely used as cryotherapy in treating warts, including genital warts, it is interesting to note that hyperthermia seems to have an advantage as it is not destructive, but, rather, appears to stimulate antiviral and immunological pathways that are reminiscent of the use of imiquimod. This study provides an elegant explanation for the observed clinical effects of hyperthermia on warts. What is unclear is whether APOBEC3A and APOBEC3G expression contribute not only to editing HPV and limiting its replication, but also whether these mutations increase immune responses against the virus. Hyperthermia, in contrast to cryotherapy, would be an elegant way to expose the virus in a meaningful way to immune reactivity and even prevent recurrences, an effect similar to that of imiquimod when used to treat genital warts.

http://www.sciencedirect.com/science/article/pii/S0022202X17301033

Ellagic acid and Annona Muricata vs. HPV and L-SIL

Ellagic acid (EA) and Annona Muricata (AM) have antioxidant, anticarcinogenic and antiviral activity demonstrated by in vitro models. This pilot study investigated the in vivo potential anti-viral activity in women affected by Low squamous intraepithelial lesion (L-SIL) related to high risk human papilloma virus (HR-HPV), and the ability to modify the oncoproteins expression in the cervical lesion thickness. Sixty women affected by HR-HPV related L-SIL, were randomly divided into two groups: group A (n = 30) supplemented with EA (16 mg) + AM (100 mg) 2 times daily for 6 months and group B (n = 30) administered with placebo. HR-HPV clearance was obtained in 74% of cases in group A compared to 25% of cases in group B (p = 0.001) and p21 expression in LSIL thickness increased in 63.2% of cases in group A compared to 20% in group B (p = 0.03). AE/AM supplementation significantly induces HR-HPV elimination and stimulates p21 expression in LSIL thickness.

http://www.sciencedirect.com/science/article/pii/S1756464617303225

2018 UPDATE 2:

Check clinical trials about Panavir, antiviral medicine made in Russia:

http://poi555.com/2018/01/panavir-from-russia-alternative-treatment-for-hpv-and-genital-warts/

YOU CAN BUY PANAVIR AT OTC ONLINE STORE

2018 UPDATE 3:

Combine Cryotherapy or Podophyllotoxin (to remove warts) with Inosine Pranobex (to lower recurrences):

This study evaluates the effectiveness of immunomodulating drug isoprinosine in a comprehensive treatment of genital warts in men. Most of the patients were aged 20-30 years. The combination therapy was found to have long term effectiveness. In the group of patients undergoing only destructive methods of treatment relapse after 8 month follow-up was diagnosed in 32% and in patients of the combination therapy group (destruction plus isoprinosine) – in 7% of patients. The pharmacological action of the drug (immunostimulating, antiviral) and the effectiveness of its combination with destructive therapies justify the use of inosine pranobex (isoprinosine) both in the complex therapy of genital warts and for the prevention of the disease recurrence.
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