Genital Warts caused by HPV – treatment, recurrence, research 2018

What should you know about genital warts caused by HPV?

Anogenital warts typically develop approximately 2–3 months after HPV infection (almost all caused by types 6 or 11); however, not all persons infected with HPV types 6 and 11 develop genital warts. Anogenital warts should be assessed by a clinician and can be treated, although many warts (20–30%) regress spontaneously. Recurrence of anogenital warts within 3 months is common (approximately 30%), whether clearance occurs spontaneously or following treatment.

Read the whole manual about HPV and genital warts:

https://www.cdc.gov/vaccines/pubs/surv-manual/chpt05-hpv.html

What is the most effective treatment against genital warts?

The most effective treatment (with the lowest recurrences) is called Photodynamic Therapy. Unfortunately this treatment is not available in the Western world. I mean: it is possible to get Photodynamic Therapy against i.e. ACNE on face, but it’s not possible to get it against genital warts. Why? I have no idea. Maybe it is a some kind of conspiracy? Anyway the fact is one: HPV virus hides in the skin, and it is possible to eradicate it during a few ALA-PDT treatments.

There were many clinical trials about Photodynamic therapy, but usually in China. You can check this PDF file:

https://www.cdc.gov/std/tg2015/evidence-tables/hpvtableevidence-genitalwarts-2015.pdf

What is the biggest problem with genital warts?

The biggest problem with genital warts is that they can come back, especially in the first months after their show up. All available methods (Cryotherapy, Podophyllotoxin, Aldara, Veregen…) have high recurrence rates.

What can you do to lower genital warts recurrence rate?

You can take medicinal mushrooms to boost your immune system (for example:  Coriolus versicolor and Reishi had 88% clearance rate after 2 months, during one clinical trial).

You can try food supplements like Ellagic Acid and Annona Muricata extract.  In one clinical trial EA+AM gave 74% HPV clearance rate after 6 months.

You can try use Panavir gel topically. Panavir is an antiviral medicine created in Russia. It works antiviral and immunostimulating. There are many russian clinical trials about its effectiveness.

http://poi555.com/2018/01/panavir-from-russia-alternative-treatment-for-hpv-and-genital-warts/

You can try hypethermia (44-45 celsius degree) on your genitals, but it might be hard to get this treatment in any clinic.

You can combine removing warts with taking Inosine Pranobex (3g daily for 4 weeks).

If you have strong recurrences – you should check your glucose level in blood. If you have diabetes, then you should know that there is correlation between the strength of HPV/number of recurrences and diabetes.

So what can you do?

Option A:

You can go to China and try to get Photodynamic Therapy (ALA-PDT) against genital warts. That’s the most expensive option.

Option B:

You can try Cryotherapy or Podophyllotoxin, and be mentally prepared for recurrences.

Option C:

You can try Cryotherapy or Podophyllotoxin, and 1 immune-booster (i.e. medicinal mushrooms, Ellagic acid + Annona Muricata extract)

Option D:

You can try Cryotherapy or Podophyllotoxin, 1 immune-booster and – topically – Panavir gel. Panavir gel should be applied 2 times daily (5 days before the treatment, 10 days after the treatment).

YOU CAN BUY PANAVIR AT OTC ONLINE STORE

Option E:

Combine Cryotherapy or Podophyllotoxin with Inosine Pranobex: 3g daily (1g in the morning/afternoon/evening) for 4 weeks. If you do this, then the chances for recurences are as low as 6-7%.

What about ALDARA?

If you are a man, then it’s a total waste of time.
If you are a woman, then you can try it (it has 60% effectiveness in females).

What about ACV, Thuja, homeopathic medicines?

Forget about it. It’s your health. Don’t waste your time on methods without any clinical trials. You can check Google Scholar and search for clinical trials.

Maitake (Grifola frondosa) vs. cancer

Maitake D (MD)-Fraction is a highly purified soluble β-glucan derived from Grifola frondosa (an oriental edible mushroom). Intraperitoneal (i.p.) injection of MD-Fraction has been reported to inhibit tumor growth via enhancement of the host immune system. In this study, we demonstrated that oral administration of MD-Fraction as well as i.p. injection significantly inhibited tumor growth in murine tumor models. After oral administration, MD-Fraction was not transferred to the blood in its free form but was captured by antigen-presenting cells such as macrophages and dendritic cells (DCs) present in the Peyer’s patch. The captured MD-Fraction was then transported to the spleen, thereby inducing the systemic immune response. Our study showed that MD-Fraction directly induced DC maturation via a C-type lectin receptor dectin-1 pathway. The therapeutic response of orally administered MD-Fraction was associated with (i) induced systemic tumor-antigen specific T cell response via dectin-1-dependent activation of DCs, (ii) increased infiltration of the activated T cells into the tumor and (iii) decreased number of tumor-caused immunosuppressive cells such as regulatory T cells and myeloid-derived suppressor cells. Our preclinical study suggests that MD-Fraction is a useful oral therapeutic agent in the management of patients with cancer.

In summary, our results demonstrated that orally administered MD-Fraction inhibits tumor growth by (i) inducing the systemic tumor-antigen specific T cell response via the dectin-1 dependent activation of DCs, (ii) increasing the infiltration of the activated T cells into the tumor and (iii) decreasing tumor-linked immunosuppressive elements such as Tregs and MDSCs. Our preclinical study advocates the implementation of MD-Fraction as an oral therapeutic agent in the management of patients with cancer.

http://onlinelibrary.wiley.com/doi/10.1002/ijc.27999/full

Where to buy medicinal mushrooms? Order mushroom extracts from China

What you should know about medicinal mushroom extracts:

– buy only hot water mushroom extracts OR alcohol mushroom extracts
– avoid powdered mushroom because your body will not digest “chitin”
– avoid powdered mushrooms because they almost don’t have any active ingredients
– hot water extraction is the only way for breaking polysaccharides out of indigestible mushroom cells
– seriously, powdered mushrooms are not better than “placebo”
– only extraction provides concentrated polysaccharides
– only extraction provides good concentration of bioavailable ingredients
– read this article about five major medicinal mushrooms: “Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology”
https://ww.ncbi.wnlm.nih.gov/pmc/articles/PMC4684115/

Where to buy good quality medicinal mushrooms extracts?

There are many companies selling “food suplements” with medicinal mushrooms. Unfortunetly they are extremly overpriced and often contain powdered mushrooms instead of mushroom extracts. Many companies sell products that are not better than “placebo”. It’s because your body will not digest chitin from powdered mushrooms.

Fortunetly you can order mushroom extracts from China.

A few months ago I was looking for a good bio-technology company from China. I’ve requested informations from 15-20 sellers available on AliBaba and AliExpress. That’s how I found XI’AN NATE BIOLOGICAL TECHNOLOGY CO.,LTD.

They gave me the answers to all my questions and they had real knowledge about mushroom extracts. That’s why I decided to buy Coriolus Versicolor (Trametes Versicolor) extract from them. I paid via Western Union and a few days later I got my package, via FedEx, without any problems.

http://www.natesw.com/

That’s why I decided to share my knowledge with you and I asked them for actual price list for all medicinal mushrooms extracts.

Prices below are for 200 kgs, but you can order 1 kg too. Of course the price for 1 kg will be higher.

Item name Specifications / Active ingredients Ref.Qty.kg USD/kg FOB
Chaga mushroom extract (from fruiting body) Polysaccharide>40%,triterpene>2%, Betulinic acid >2% 200kg $ 74.0/kg

Polysaccharide>20%,triterpene>6% 200kg $ 132.0/kg
Reishi mushroom spore powder Wall broken ratio>98% 200kg $55.0/kg
Reishi mushroom extract (from fruiting body) Polysaccharide>30%,triterpenoid>2% 200kg $57.0/kg

Polysaccharide>40%,triterpenoid>2% 200kg $70.0/kg
Polysaccharide>10%,triterpenoid>4% 200kg $86.0/kg
Polysaccharide>10%,triterpenoid>8% 200kg $125.0/kg
Cordycep sinensis extract(CS-4 mycelium) Polysaccharide>30%,Adenosine 0.5 200kg $65.0/kg
 Polysaccharide>40%,Adenosine 1.0 200kg $74.0/kg
Cordyceps militaris extract (from fruiting body) Polysaccharide>40%,Adenosine 0.5 200kg $ 73.0/kg

Polysaccharide>50%,Adenosine 1.0 200kg $ 85.0/kg
Polysaccharide>20%,Cordycepin 1.0% 200kg $ 97.0/kg
Polysaccharide>15%,Cordycepin 3.0% 200kg $ 302.0/kg
Lion’s mane mushroom extract (from fruiting body) Polysaccharide>40% 200kg $ 64.0/kg
 Polysaccharide>50% 200kg $ 75.0/kg
Coriolus versicolor / Turkey tail extract Polysaccharide>40% 200kg $ 65.0/kg
 Glycopeptide 30%,protein 10% 200kg $ 86.0/kg
Shiitake mushroom extract (from fruiting body)

Polysaccharide>40% 200kg $54.0/kg
 Polysaccharide>50% 200kg $62.0/kg
Maitake mushroom extract Polysaccharide>40% 200kg $ 67.0/kg
Maitake mushroom extract MD>30%,Protein10% 200kg

$114.0/kg

Agaricus blazei extract Polysaccharide>40% 200kg $ 55.0/kg
Phellinus igniarius extract (from fruiting body)

Polysaccharide>20%,triterpenoid>1% 200kg

$57.0/kg

 Polysaccharide>40%,triterpenoid>2% 200kg

$99.0/kg

Tremella fuciformis extract Polysaccharide>40% 200kg

$65.0/kg

Enoki mushroom extract Polysaccharide>40% 200kg

$67.0/kg

Coprinus comatus extract Polysaccharide>40% 200kg

$65.0/kg

Agrocybe cylindraceaextract Polysaccharide>40% 200kg

$64.0/kg

Antrodia Camphorata extract Polysaccharide>40% 200kg

$83.0/kg

Poria cocos extract

Polysaccharide>40% 200kg

$54.0/kg

Polyporus umbellatus extract Polysaccharide>40% 200kg

$58.0/kg

AHCC

Alpha-glucan>40%

200kg

$89.0/kg

Agaricus bisporus extract Polysaccharide>40%

200kg

$58.0/kg

Chantarelle extract Polysaccharide>40%

200kg

$56.0/kg

Boletus edulis extract Polysaccharide>40%

200kg

$67.0/kg